Diabetes Education and Research Center
Back Chats
On Wed Jul 14 17:42:56 2004 M () said:
I do think positive, but you can't
live in a dream world either. Bad things happen to good people every day. I've
tried getting on the list and can't. But I'm trying to get in a program in Miami
in a research program. I'm willing to be a giena pig just to get in. Maybe where
you live it's eaiser to get on the list or something. But it's not that easy
here. My doctor told me that the anti rejection pills alone a 1,000 a month and
sometimes the side effects can be bad. And alot of insurance won't pay for it.
I'm not trying to be a downer just living in the real world.
On Wed Jul 14 16:51:53 2004 mandy () said:
but M you should think positive
:)
On Wed Jul 14 16:34:32 2004 M () said:
Mandy, I want to believe that and I'm
not trying to be a downer about it.And if your on the list then good luck to
you, I hope you get it and every thing works out ok for you. I'm just saying
that it doesn't happen that way for everyone.
On Wed Jul 14 12:16:55 2004 MANDY () said:
CARLOS YOU HAVE TO HAVE YOUR
BLOOD SUGAR AS CLOSE TO NORMAL AS POSSIBLE. THE NORMAL READING IS BETWEEN
5-7mmols, WELL THATS WHAT IS IN ENGLAND, I AM NOT SURE WHAT YOUR READINGS ARE.
HOPE THAT HELPS A LITTLE.
On Wed Jul 14 12:14:48 2004 mandy () said:
M THATS NOT TRUE, IT'S NOT A
MONEY THING I AM ON THE WAITING LIST FOR ISLET TRANSPLANT, AND BELEIVE ME I AM
NOT RICH IN THE FINANCIAL WAY, SO STOP PUTTING A DOWNER ON THE FACT THERE IS A
CURE JUST AROUND THE CORNER.................FOR EVERYONE :)
On Wed Jul 14 11:26:25 2004 carlos (latvijo@aol.com) said:
I have a
question, how high my sugar level revel if Iam a diabetis
On Wed Jul 14 10:13:15 2004 M () said:
I think there is alot of stuff out
there that is just around the corner. But who will get to benifit from it? I
think that it's a money game and not who needs the help the most, now. They talk
about how much progress they are making but we never see the results. It would
be nice if this stuff would get out there and some of us could benifit from it.
The ones that have had it for years they don't want to help, because the damage
is already done, they want the people that haven't had it long, that way they
can help them before the damage get's to bad.Therefore they can say there cure
works.
On Tue Jul 13 14:04:42 2004 MANDY () said:
you never know Sam a break
through could be just around the corner. :)
On Tue Jul 13 12:17:12 2004 Sam () said:
Mandy; Thanks for the info...I know
I have an auto-immune disease which caused type 1 diabetes, hypothyroidism,
rheumatoid arthritis, etc. But at 62, with years ahead for research, that's it
for me. FYI...i went back on the insulin pump, but learned...for me...that I can
use Lantus for a weekend, or so...and stay off the pump for a short time without
problems.
On Mon Jul 12 12:03:02 2004 Mandy (Mandi.d@dsl.pipex.com) said:
Look what I
came across today as I was reading through the bbc
news.............................. Gene mutation linked to diabetes People with
type 1 diabetes need to monitor their blood sugar levels US scientists have
found a fault in a newly discovered gene that may explain why some people have
type 1 diabetes. The SUMO-4 gene helps regulate the body's immune system that
defends against infection. Dr Jin-Xiong She and colleagues at the Medical
College of Georgia examined nearly 1,000 diabetic families. The findings are
published in the journal Nature Genetics. Other genes have been identified that
contribute to type 1 diabetes. For the last 10 years, Dr She and colleagues have
been looking at how the immune system and the environment work together to cause
type 1 diabetes. It's the first gene in which we know how it contributes to the
disease Dr Jin-Xiong She, lead researcher In diabetes the body cannot convert
the glucose in its blood into energy because the hormone insulin, which enables
this to take place, is either not produced or does not work properly. People
with type 1 diabetes have to take insulin to correct this. Dr She and colleagues
looked at SUMO-4 because of its action on the immune system. They found the
family members with type 1 diabetes were more likely to have a certain natural
mutation of this gene than other non-diabetic family members. Further studies by
the team found when the mutation encountered an environmental trigger, such as a
bacterial or viral infection, it threw off the usual well-balanced activity of
the body's immune system. This launched a response from the immune system that
would eventually attack the person's own tissue. Attack This type of self-attack
is what causes diseases such as diabetes and rheumatoid arthritis which are
known as autoimmune diseases. The researchers said the mutation made the immune
system more reactive to environmental triggers. SUMO-4 controls the activity of
a molecule called NFkB. This, in turn, controls the activity of proteins called
cytokines that regulate the intensity and duration of the body's immune
response. It was already known that cytokines have a role in type 1 diabetes and
other autoimmune diseases. What wasn't known was the cause of the excessive
cytokines in these conditions. Dr She said: "It's the first gene for which we
know how it contributes to the disease." The faulty SUMO-4 gene enables more
cytokines to be made and directs the revved up immune response at the cells in
the pancreas that make insulin. A cure? Dr She said their work should help
people with diabetes. "This helps us understand how type 1 diabetes works and we
can use this improved understanding to better predict who will get the disease."
He said this should also enable them to develop new treatments for type 1
diabetes. Dr Martin Buckley, research fellow at the diabetes centre in Bolton,
said: "It's an interesting discovery but obviously more work needs to be done in
the future to find out how this could be translated into a potential medical
cure for type 1 diabetes." He said this could be many years away. Professor
Simon Howell, Research Advisor for Diabetes UK said: "This is interesting
research and whilst we don't know exactly what causes diabetes we know it is a
combination of environmental and genetic factors. "This research is trying to
identify the genes responsible for Type 1 diabetes and may be an important step
forward in this area."
On Sun Jul 11 17:22:02 2004 () said:
YEAH WHATEVER !!!!! On Sun Jul 11
00:05:50 2004
On Sun Jul 11 00:05:50 2004 In Reply To (Fri Jul 9 09:15:21 2004 M) said:
LIFE IS NOT A JOURNEY TO THE GRAVE WITH THE INTENTION OF ARRIVING SAFELY IN
A PRETTY AND WELL PRESERVED BODY. BUT RATHER TO SKID IN BROADSIDE, THOROUGHLY
USED UP, TOTALLY WORN OUT, AND LOUDLY PROCLAIMING - "WOW----WHAT A RIDE!"
On Fri Jul 9 15:32:31 2004 mandy (mandi.d@virgin.net) said:
When you say you
have nerve damage in your stomach, what do you mean? Sorry I find it interesting
and I am learning all the time. I have been Insulin Dependant for 6 years
now.
On Fri Jul 9 09:15:21 2004 M () said:
I"ve been insulin depent for about 20
years. Have trouble with alot of nerve damage. One in the feet and two in the
stomach. I also have fibromyalgia, throid diease, capel tunnel both wrists and
am a complete mess. I hope all you new people out there take care of yourselfs
because it is really important. When you start to pay the price it's not pretty.
It's very painful. I've worked hard all my life and played hard so I can get old
and suffer.
On Wed Jul 7 16:22:55 2004 M () said:
It's a diabetic pill that makes the
insulin stick to the cells. I'm insulin resistence right now and he said the
insulin is just floating around and this will make it stick to the cells which
is suppose to lower the bs. My sugars have been lower today then they have been.
Lately I can take all the insulin I want and it doesn't seem to lower the bs. I
hope this works.
On Wed Jul 7 09:08:45 2004 mandy () said:
M I have never heard of that? What
is it?
On Tue Jul 6 18:17:17 2004 M () said:
My doctor just put me on actos to take
with my isulin. Is anyone else here taking it?
On Sun Jul 4 12:20:49 2004 patty (www.patticke52@hotmail.com) said:
Same
here mandy my readings really do a number on me sometimes,other times I get in
denial then maybe a problem will come up such as a red toe or a sore that won't
heal that shocks me back into knowing what could happen. I've been a diabetic
for 23 years and I've been up and down with my glucose readings but now that I'm
older and I'm a little more wiser knowing the risk of what could happen. I still
fall sometimes but I don't stay down so long , its not easy thats for sure but
we do need to try our best to keep our readings normal as possible. Thanks for
your response, and take care.
On Sun Jul 4 04:00:20 2004 mandy () said:
I have seen the effects of
diabetes of what it does when you dont take care of yourself, I see at least one
- two people come down to theatre to have something amputated, it makes realise
that I do have to look after myself, even though it is tough.
On Sat Jul 3 20:46:04 2004 patty (www.patticke52@hotmail.com) said:
Thanks
for the response O. I guess me being a diabetic also is the reason it hurt me so
bad , I've seen people with this diease without their feet and legs and also
their eyesight its not a joking matter no diease is a joking matter.For those
who want to make fun and joke , I don't wish it own them, but they need to walk
a mile in our shoes that maybe some of us walk in when we had our feet and
legs.
On Sat Jul 3 17:08:27 2004 () said:
Well said Patty, some people take life
as a joke!! I just hope people no the sick animals like that sad individual
never has to go through what others do.
On Sat Jul 3 16:27:36 2004 patty (www.patticke52@hotmail.com) said:
Just a
reply on what this child wrote thats so ugly,you must not have anybody you love
with this diease, if so i don't think you would be quite so ugly and
incompassionate. when you've had love ones to sat and cry because their feet or
legs have to cut off its not a very funny sight. I hope you don't have to go
thru that ever, but you know sometimes we have to eat our words. I feel so sorry
for you!!!!
On Thu Jul 1 02:56:41 2004 mandy () said:
My biggest fear is losing my
sight, it really scares me.
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